KEGG   REACTION: R04676
Entry
R04676                      Reaction                               
Name
17alpha,20alpha-dihydroxycholesterol:oxygen oxidoreductase (side-chain-cleaving)
Definition
17alpha,20alpha-Dihydroxycholesterol + 2 Oxygen + 4 H+ + 4 Reduced adrenal ferredoxin <=> 17alpha-Hydroxypregnenolone + 4-Methylpentanal + 3 H2O + 4 Oxidized adrenal ferredoxin
Equation
C05499 + 2 C00007 + 4 C00080 + 4 C00662 <=> C05138 + C02373 + 3 C00001 + 4 C00667
Comment
two-step reaction (similar to R04854+R03933)
Reaction class
RC01193  C05138_C05499
RC01543  C02373_C05499
Enzyme
1.14.15.6
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6
     R04676  17alpha,20alpha-Dihydroxycholesterol + 2 Oxygen + 4 H+ + 4 Reduced adrenal ferredoxin <=> 17alpha-Hydroxypregnenolone + 4-Methylpentanal + 3 H2O + 4 Oxidized adrenal ferredoxin
Orthology
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (396)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (395)   
All databases (410)   

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